What is a Serum Blood Collection Tube?

What is a Serum Blood Collection Tube

Serum Blood Collection Tubes are vacuum blood collection tubes that do not contain anticoagulants, preservatives, or separating materials. Used to collect serum for specific laboratory tests and isolate serum after phlebotomy for clinical chemistry, immunology, and therapeutic drug testing. Coagulants work to speed up blood clotting, and the use of coagulation vessels reduces turnaround time. The tube is a disposable negative pressure vacuum glass tube or a disposable negative pressure vacuum plastic tube that can realize quantitative blood collection and needs to be used with a venous Blood Collection Needle.

Its principle is a negative-pressure vacuum blood collection tube, which uses its negative pressure to automatically and quantitatively collect venous blood samples. Human venous blood is drawn into the blood sample container through the Blood collection needle under the negative pressure of the vacuum blood collection tube. One venipuncture can collect multiple tubes without leakage. 

Blood Collection Tubes

The volume of the lumen connected to the blood collection needle is small, the influence on the blood collection volume is negligible, and the probability of backflow is relatively small. If the lumen volume of the butterfly blood collection needle is large, it will consume part of the vacuum of the blood collection tube, thereby reducing the blood collection volume.

Siny Medical SST Tube

Detection: Serum tubes can be used for clinical, biochemical, immunological, and serological testing.

Additives: According to different additives, serum blood collection tubes can be divided into three different types (common, clot activator, gel and coagulant). They are plain tubes, procoagulant tubes, gel and coagulation activator tubes.

Additive free medical test tube for serum collection

Material: The main materials used are PS, PP, and PET

Tube size (mm): 13*75, 13*100, 16*100.

Tube colours: red non-additive tubes, orange procoagulant tubes, and yellow top tubes.

Serum TubeNo Additive TubeNoneRed
Pro-coagulation TubeClot ActivatorOrange
Gel & clot Activator TubeGel & Clot ActivatorYellow

Uses of Blood Collection Tubes of Different Colors

Serum Tubeno additive tubeNoneRed
Pro-coagulation TubeClot ActivatorOrange
Gel & clot Activator TubeGel & Clot ActivatorYellow
Plasma TubeGlucose TubePotassiumOxalate/SodiumFluoride Or EDTA/SodiumFluorideGrey
PT Tube3.2% Sodium citrateBlue
PT TubeGel & 3.2% Sodium citrateBlue
Heparin TubeHeparin Lithium,Heparin SodiumGreen
Gel & Heparin TubeGel & Heparin Lithium, or Heparin SodiumGreen
Whole Blood TubeEDTA TubeEDTA-K2.EDTA-K3Purple
ESR Tube3.8% Sodium citrateBlack

Sinymedical is your high-standard OEM manufacturer of serum separation tubes in China. Siny Medical is a blood collection tube factory, supplier, and manufacturer with a history spanning more than 20 years. Welcome to contact us to customize, develop and manufacture

Blood Collection Tube Classifications

Red blood collection tube, normal or fast serum tube

The labeling of ordinary serum tubes and fast serum tubes involves a distinction between those marked with or without a procoagulant, utilizing red and orange colors to highlight the differences. The facilitation of blood clotting is attributed to the presence of a procoagulant. The use of a procoagulant achieves the acceleration of blood clotting.

Applicable sample type: Serum

Uses: PCT, mycoplasma antibodies, gastrin ANCA, blood cytomegalovirus antibody, human epididymal epithelial secretory protein, serum protein electrophoresis, RA five, TB-AD tuberculosis antibody.

Light green blood collection tube Plasma separation tube

Heparin possesses a mucopolysaccharide nature with a pronounced negative charge on its sulfate group. It forms a composition with sodium or lithium heparin and a gelling agent. This characteristic renders the antithrombin three-inactivating serine protease more potent.

Applicable sample type: Plasma

Uses:  B27, blood ammonia, BNP (B-type natriuretic peptide)

A light blue blood collection tube Trace element tube

Includes procoagulant (plastic tube, serum) and non-procoagulant (glass tube, serum) additives, as well as sodium heparin, EDTA Na2, and EDTA K2.

Uses: trace elements, toxicology and nutritional chemistry tests.

Green blood collection tube Heparin anticoagulation tube

Blood collection adapter green hat blood collection vessel

The blood collection tube has heparin added to it. Heparin directly exerts the antithrombin effect, resulting in the prolongation of the clotting time of the specimen.

Applicable sample types: Whole blood, plasma

Use: Sedimentation, general biochemical determination, red blood cell fragility test, blood gas analysis, and red blood cell pressure test.

Purple blood collection tube EDTA anticoagulant tube

EDTA anticoagulant, the routine blood test employs this particular anticoagulant. other anticoagulants, EDTA Tubes has minimal impact on both blood coagulation and cell morphology

Grey blood collection tube Sodium oxalate/sodium fluoride blood glucose test tube

Sodium fluoride, potassium oxalate, sodium fluoride, and sodium heparin are the ingredients in the tube. One beneficial consequence of sodium fluoride, a mild anticoagulant, is that it can stop the breakdown of blood glucose.

To create a solution that prevents blood coagulation and inhibits sugar decomposition for 23 days, combine 4mg of the sodium fluoride + potassium oxalate/sodium fluoride + sodium heparin mixture in 1 ml.

Sample type: whole blood, plasma

Uses: 2ml: blood routine, reticulocytes, glycated hemoglobin

A light blue blood collection tube sodium citrate (sodium citrate) blood collection tube

Containing 3.2% or 3.8% sodium citrate (sodium citrate), please take care to collect enough blood to ensure the accuracy of test results. Please invert and mix 5-8 times immediately after blood collection.

Applicable specimen type: Whole blood, plasma

Use: Prothrombin time, prothrombin time, activated partial thromboplastin time, and fibrinogen are examples of fibrinolytic systems.

Golden yellow blood collection tube Inert separation pro-coagulation tube

To speed up blood coagulation and reduce test time, apply a coagulant to the tube wall and refrain from using a 37℃ water bath. Separation gel and PET tube have a good affinity and play a role in isolation.

Applicable specimen type: Serum

Use 3ml: Biochemical items, digoxin concentration, cardiac enzymes, amylase, thyroid function, full thyroid function, free thyroid function.

5ml: C-reactive protein (CRP immunity, red and yellow), high-sensitivity C-reactive protein (hs-CRP)

A black blood collection tube Sodium citrate blood sedimentation test tube

Contains 3.2% (0.109 mol/L)-3.8% sodium citrate (sodium citrate) with a volume ratio of anticoagulant to blood of 1:4.

Heparin, as an anticoagulant, can alter the potential of red blood cells.

Applicable sample type: Whole blood

Use: Blood sedimentation


What color tube is used for serum?

The distinctive red color indicates the absence of anticoagulants or clot activators, allowing the blood to clot naturally. This clotting process separates the serum from the blood cells, facilitating accurate diagnostic testing.

What are serum tubes for blood collection?

Specialized containers, recognized as red-top tubes, designed for collecting blood samples for diagnostic testing, play a crucial role in maintaining the integrity of serum—the liquid component of blood acquired after coagulation.

What is the name of the serum tube?

A red-top tube is the designation for a tube specifically designed for serum collection. The nomenclature originates from the tube's distinct red color, which signifies its purpose of allowing blood to clot and separating the serum for analysis.

What container is used for serum collection?

The container used for serum collection is the red-top tube. It is a standard in laboratories and healthcare settings for obtaining blood samples for various diagnostic tests. The absence of additives in the tube ensures that the serum remains in its natural state, providing accurate results during laboratory analysis.

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